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Industry / Pharma & Biotech

A quantitative operating layer for computational discovery.

LargeQuant brings molecular candidates, numerical property models, docking, developability, synthesis planning, experimental evidence and reproducibility into one discovery programme.

The operating challenge

Computational scale only matters if it improves experimental choice.

The laboratory is the scarce resource. Discovery teams can generate or screen far more molecular ideas than they can synthesize and assay, so the platform must help decide which candidate deserves the next experiment and then learn from the measured result. LargeQuant is designed around that closed loop.

HumanTwin · Powered by LargeQuant

Put biological model state, evidence and uncertainty in the same visual context.

HumanTwin provides the interactive anatomical layer. LargeQuant provides the quantitative evidence envelope underneath it, so a region can be inspected together with model state, evidence count, uncertainty and provenance.

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Where LargeQuant fits

High-value quantitative workflows.

Hit and lead prioritisation

Combine quantitative endpoints, docking evidence, measured assays and multi-objective constraints to rank compounds.

QSAR / property modelling

Fit quantitative property models where endpoint evidence is sufficient and retain model/evaluation provenance.

Docking workflows

Execute prepared docking cases through trusted adapters and preserve extracted scores and artifacts.

Developability screening

Evaluate recorded descriptor constraints alongside target-oriented predictions.

Synthesis & experiment planning

Turn selected compounds into structured synthesis and assay plans linked to the campaign record.

Measured-result feedback

Ingest assay outcomes as measured evidence and use them to update candidate progression and the next research round.

Operating workflow

Connect the domain model to the evidence and decision layer.

01Define target and assay endpoints.
02Register compounds and measured evidence.
03Fit quantitative property models.
04Run docking/developability screens where appropriate.
05Select compounds under multiple objectives.
06Plan synthesis and experiment.
07Ingest assay results.
08Re-rank and continue the campaign.
Platform capabilities

Quantitative infrastructure around your domain expertise.

Drug campaign system

Targets, compounds, assays, stages and candidate evaluations.

QSAR

Numerical molecular property modelling for supported endpoints.

Docking adapters

Trusted execution around prepared docking artifacts.

Developability

Descriptor-based quantitative screening.

Molecular proposals

Bounded chemistry-tool integrations for candidate generation.

Evidence loop

Measured assay results flow back into the programme without being conflated with predictions.

Data & systems

Designed to connect to the stack you already operate.

  • Molecular structure collections
  • Assay / screening databases
  • Cheminformatics toolchains
  • Docking runtimes and prepared receptor/ligand artifacts
  • Retrosynthesis/synthesis planning tools
  • Laboratory result feeds
Teams

Built for cross-functional quantitative work.

  • Computational Chemistry
  • Medicinal Chemistry
  • Drug Discovery Informatics
  • Translational / Discovery Biology
  • Platform R&D
  • Scientific Data & AI Teams
Evidence & governance

Keep the basis of the decision inspectable.

Computed affinity, QSAR output, descriptor screens and measured assay values remain separate evidence classes. That separation is essential for using computation to guide experiments without presenting prediction as measurement.

Explore evidence & provenance →
Pharma & Biotech

Bring your real data, models and decision constraints.